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	<title>Geen gevolge &#187; Genomics</title>
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		<title>Applications &amp; Bottlenecks In Next Generation Sequencing, Day 2</title>
		<link>http://www.gene-effects.co.uk/af/2013/applications-bottlenecks-in-next-generation-sequencing-day-2/</link>
		<comments>http://www.gene-effects.co.uk/af/2013/applications-bottlenecks-in-next-generation-sequencing-day-2/#comments</comments>
		<pubdate>Wed, 18 Dec 2013 08:30:10 +0000</pubdate>
		<dc:creator>Paul Denny</dc:creator>
				<category><![CDATA[Genomics]]></category>
		<category><![CDATA[Science Communication]]></category>

		<guid ispermalink="false">http://www.gene-effects.co.uk/?p=1092-af</guid>
		<description><![CDATA[This word cloud shows the words that people used in the ice-breaking session, that I mentioned in my last post, &amp;nbsp;to describe what they hoped to gain from the conference. On Day 2, our Keynote speaker was: Dr Anneke Seller, Oxford Genetics: Clinical utility; actionable #NGS diagnosis for patients &#38; families http://t.co/0mmrSx1Dd5 #ngsmanchester &#8212; Paul [...]]]></description>
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		<title>Applications &amp; Bottlenecks In Next Generation Sequencing</title>
		<link>http://www.gene-effects.co.uk/af/2013/applications-bottlenecks-in-next-generation-sequencing/</link>
		<comments>http://www.gene-effects.co.uk/af/2013/applications-bottlenecks-in-next-generation-sequencing/#comments</comments>
		<pubdate>Thu, 21 Nov 2013 08:15:14 +0000</pubdate>
		<dc:creator>Paul Denny</dc:creator>
				<category><![CDATA[Genomics]]></category>
		<category><![CDATA[Science Communication]]></category>

		<guid ispermalink="false">http://www.gene-effects.co.uk/?p=1027-af</guid>
		<description><![CDATA[After months of preparation and the occasional sleepless night, November 5th arrived. &amp;nbsp;It wasn’t only Bonfire Night, but also the beginning of a&amp;nbsp;two-day conference, focusing on NGS in&amp;nbsp;clinical genetics laboratories. &amp;nbsp;Organised by my colleagues and friends from biotexcel and myself, it was&amp;nbsp;held in the&amp;nbsp;Manchester Conference Centre, in, naturally enough, Manchester, UK. In order to break [...]]]></description>
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		<item>
		<title>So, What Do Your Genes DO?</title>
		<link>http://www.gene-effects.co.uk/af/2013/so-what-do-your-genes-do/</link>
		<comments>http://www.gene-effects.co.uk/af/2013/so-what-do-your-genes-do/#comments</comments>
		<pubdate>Tue, 12 Nov 2013 20:20:59 +0000</pubdate>
		<dc:creator>Paul Denny</dc:creator>
				<category><![CDATA[Disease Models]]></category>
		<category><![CDATA[Genomics]]></category>
		<category><![CDATA[Target discovery]]></category>

		<guid ispermalink="false">http://www.gene-effects.co.uk/?p=604-af</guid>
		<description><![CDATA[Genes are not passive. &amp;nbsp;They are the target of molecular &#8220;dimmer switches&#8221;; typically (but not always) specific proteins, which dial up or turn down their activity. &amp;nbsp;Most genes are translated into proteins, but discovering the true&amp;nbsp;role of&amp;nbsp;those proteins, in the life of a cell or a whole organism, is still one of the great challenges [...]]]></description>
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		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Some of our genes are missing&#8230;but which ones?</title>
		<link>http://www.gene-effects.co.uk/af/2013/some-of-our-genes-are-missing-but-which-ones/</link>
		<comments>http://www.gene-effects.co.uk/af/2013/some-of-our-genes-are-missing-but-which-ones/#comments</comments>
		<pubdate>Tue, 28 May 2013 07:47:23 +0000</pubdate>
		<dc:creator>Paul Denny</dc:creator>
				<category><![CDATA[Disease Models]]></category>
		<category><![CDATA[Genomics]]></category>

		<guid ispermalink="false">http://www.gene-effects.co.uk/?p=598-af</guid>
		<description><![CDATA[One can think of genes in a number of ways: At the level of the DNA &#8211; simply as a linear sequence of nucleotides, in ONE fixed order, in the &#8220;normal&#8221; state, or Again as a DNA molecule, but remember that genes in organisms, rather than in pieces of DNA in a test-tube, are subject [...]]]></description>
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		<title>Genetics Society Spring Meeting: Genomics for Health and Society</title>
		<link>http://www.gene-effects.co.uk/af/2013/genetics-society-spring-meeting-genomics-for-health-and-society/</link>
		<comments>http://www.gene-effects.co.uk/af/2013/genetics-society-spring-meeting-genomics-for-health-and-society/#comments</comments>
		<pubdate>Tue, 14 May 2013 07:37:27 +0000</pubdate>
		<dc:creator>Paul Denny</dc:creator>
				<category><![CDATA[Genomics]]></category>
		<category><![CDATA[Science Communication]]></category>

		<guid ispermalink="false">http://www.gene-effects.co.uk/?p=875-af</guid>
		<description><![CDATA[The aim of of the meeting was to begin to answer the question: &#8220;What will be the impact of large-scale sequencing of human populations in the 21st Century?&#8221; Held at The Royal Society in London on 19th April 2013, the meeting brought together some distinguished figures from clinical genetics, population genomics, DNA fingerprinting and the [...]]]></description>
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		<item>
		<title>Moving Next-Generation Sequencing into the Clinic, part 2</title>
		<link>http://www.gene-effects.co.uk/af/2013/moving-next-generation-sequencing-into-the-clinic-part-2/</link>
		<comments>http://www.gene-effects.co.uk/af/2013/moving-next-generation-sequencing-into-the-clinic-part-2/#comments</comments>
		<pubdate>Thu, 21 Mar 2013 22:31:48 +0000</pubdate>
		<dc:creator>Paul Denny</dc:creator>
				<category><![CDATA[Genomics]]></category>

		<guid ispermalink="false">http://www.gene-effects.co.uk/?p=759-af</guid>
		<description><![CDATA[first attempt at live tweets from #ngs2013 http://t.co/SbWrGx8weI &#8212; Paul Denny (@pauldennyuk) March 12, 2013 In my last post, I summarised the first four talks from this symposium: 1st Oxford Workshop and Symposium, 4th Techgene Knowledge Network Meeting, &#8220;NGS2013 Next generation Sequencing: Bioinformatics and Data Analysis&#8221; You could also read the Tweets from the meeting [...]]]></description>
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		<item>
		<title>Moving Next-Generation Sequencing into the Clinic</title>
		<link>http://www.gene-effects.co.uk/af/2013/moving-next-generation-sequencing-into-the-clinic/</link>
		<comments>http://www.gene-effects.co.uk/af/2013/moving-next-generation-sequencing-into-the-clinic/#comments</comments>
		<pubdate>Fri, 15 Mar 2013 16:04:51 +0000</pubdate>
		<dc:creator>Paul Denny</dc:creator>
				<category><![CDATA[Genomics]]></category>

		<guid ispermalink="false">http://www.gene-effects.co.uk/?p=651-af</guid>
		<description><![CDATA[On a glorious day (but with Arctic-like winds!) earlier this week, I attended a symposium on exploiting NGS in the diagnostic genetics clinic: Off to # Ngs2013 today at Wolfson College Oxford http://t.co/SbWrGx8weI #NGS #Clinical #Dx #diagnostic #personalisedmed Should be good &#8212; Paul Denny (@pauldennyuk) March 12, 2013 The speakers were clinicians, bioinformaticians and biomedical [...]]]></description>
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