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	<title>Gene Effetti &#187; Obiettivo scoperta</title>
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		<title>Così, What Do Your Genes DO?</title>
		<link>http://www.gene-effects.co.uk/it/2013/so-what-do-your-genes-do/</link>
		<comments>http://www.gene-effects.co.uk/it/2013/so-what-do-your-genes-do/#comments</comments>
		<pubdate>Tue, 12 Nov 2013 20:20:59 +0000</pubdate>
		<dc:creator>Paul Denny</dc:creator>
				<category><![CDATA[Disease Models]]></category>
		<category><![CDATA[Genomics]]></category>
		<category><![CDATA[Obiettivo scoperta]]></category>

		<guid ispermalink="false">http://www.gene-effects.co.uk/?p=604-it</guid>
		<description><![CDATA[Genes are not passive. &amp;nbsp;They are the target of molecular &#8220;dimmer switches&#8221;; typically (but not always) specific proteins, which dial up or turn down their activity. &amp;nbsp;Most genes are translated into proteins, but discovering the true&amp;nbsp;role of&amp;nbsp;those proteins, in the life of a cell or a whole organism, is still one of the great challenges [...]]]></description>
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		<title>Come fa una mutazione in un orecchio colla fattore di trascrizione causa?</title>
		<link>http://www.gene-effects.co.uk/it/2012/how-does-a-mutation-in-a-transcription-factor-cause-glue-ear/</link>
		<comments>http://www.gene-effects.co.uk/it/2012/how-does-a-mutation-in-a-transcription-factor-cause-glue-ear/#comments</comments>
		<pubdate>Mon, 17 Sep 2012 14:01:22 +0000</pubdate>
		<dc:creator>Paul Denny</dc:creator>
				<category><![CDATA[Percorso di analisi]]></category>
		<category><![CDATA[Obiettivo scoperta]]></category>

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		<description><![CDATA[Otite media acuta, sometimes known as “glue ear”, is the most common bacterial infection in children and by 1 anno di età circa 60% di bambini hanno avuto un episodio. In alcuni casi, children develop a chronic condition, che, nonostante l'infezione guarigione, il &#8220;colla&#8221; doesn’t go away and causes deafness. &amp;nbsp;In an [...]]]></description>
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		<title>Scoperta Target in asma ad esordio infantile</title>
		<link>http://www.gene-effects.co.uk/it/2012/target-discovery-in-childhood-onset-asthma/</link>
		<comments>http://www.gene-effects.co.uk/it/2012/target-discovery-in-childhood-onset-asthma/#comments</comments>
		<pubdate>Thu, 06 Sep 2012 10:25:22 +0000</pubdate>
		<dc:creator>Paul Denny</dc:creator>
				<category><![CDATA[Obiettivo scoperta]]></category>

		<guid ispermalink="false">http://www.gene-effects.co.uk/?p=418-it</guid>
		<description><![CDATA[Asthma is caused by a combination of environmental and genetic influences, ma i fattori specifici sono poco conosciuti. Un significativo &quot;hit&quot; rilevato in un genoma-wide association scan (GWAS) for childhood asthma led a client to believe that one gene might be partially responsible. Dimostrare che questa associazione genetica realmente stava causando asma era, tuttavia, difficile. In primo luogo, [...]]]></description>
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		<title>Pathway analisi dei dati di espressione genica &#8211; riduzione della fertilità maschile / sterilità</title>
		<link>http://www.gene-effects.co.uk/it/2012/pathway-analysis-of-gene-expression-data-male-reduced-fertility-sterility/</link>
		<comments>http://www.gene-effects.co.uk/it/2012/pathway-analysis-of-gene-expression-data-male-reduced-fertility-sterility/#comments</comments>
		<pubdate>Tue, 21 Aug 2012 07:30:18 +0000</pubdate>
		<dc:creator>Paul Denny</dc:creator>
				<category><![CDATA[Percorso di analisi]]></category>
		<category><![CDATA[Obiettivo scoperta]]></category>

		<guid ispermalink="false">http://localhost:8888/?p=246-it</guid>
		<description><![CDATA[Un gruppo di animali che possono allevare e produrre prole fertile è una delle definizioni di una specie. Ciò significa che i meccanismi biologici di fertilità e infertilità sono di interesse non solo per i biologi evoluzionisti, ma anche per i medici e, naturalmente, al grande pubblico. At the Institute of Molecular Genetics in [...]]]></description>
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		<title>Scoperta Target in debolezza muscolare ereditaria</title>
		<link>http://www.gene-effects.co.uk/it/2012/target-discovery-in-inherited-muscle-weakness/</link>
		<comments>http://www.gene-effects.co.uk/it/2012/target-discovery-in-inherited-muscle-weakness/#comments</comments>
		<pubdate>Fri, 03 Aug 2012 18:56:57 +0000</pubdate>
		<dc:creator>Paul Denny</dc:creator>
				<category><![CDATA[Obiettivo scoperta]]></category>

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		<description><![CDATA[La debolezza muscolare può essere causata da una rara malattia ereditaria chiamata miopatia miofibrillare. Gonzalo Blanco’s team found a&amp;nbsp;mouse model of this disease&amp;nbsp;and wanted to identify the underlying cause of the severe muscle weakness. Il loro scopo era quello di scoprire potenziali bersagli terapeutici per tradurre in studi pre-clinici e clinici. Prima di diventare coinvolti, the disease had [...]]]></description>
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