Gene Set Enrichment Analysis is one of many approaches to the analysis of gene expression profile data and is described in a paper from workers at the Broad Institute. The basic concept was prompted by the observation that studying individual genes showing the most significant difference in expression level between two states or phenotypes is lacking [...]
Author Archives: Paul Denny
Yeej ntawm editing cov phau ntawv txoj kev kawm ntawv kev kawm
Los sis:"beginner txoj kev qhia herding miv". Xav txog qhov scenario: koj yog ib tus paub txog txoj kev kawm ntawv, nyob rau hauv ib qhov kev tshawb fawb tibneeg hu tauj coob lub koom haum thiab jib yog caw los hloov phau ntawv, tab sis cia ntawm siab uas ua hauj lwm; ces pheej yuav qhia tau tias nws yuav zoo rau koj CV. Koj pom zoo, nws yuav zoo rau koj CV, so [...]
Muab tso rau hauv Lub teeb nyem
1 Teb
Ib cov hloov hauv lub transcription tau ua kua nplaum pob ntseg li cas?
Mob ntsej rag, tej zaum kuj tau hu ua "pob ntseg lo", yog tus tshaj tug mob rau cov me nyuam thiab los 1 lub xyoo uas muaj hnub nyoog txog 60% cov me nyuam yuav tau txhaj ib. Tej zaum, cov me nyuam muaj ib yam mob mob, uas, dua li ntawm cov raug tus mob no yog kho, tus “kua nplaum” tsis txawj puas thiab ua rau cov lag ntseg. nyob rau ib qho [...]
Muab tso rau hauv Chaw tsom, Phiaj foundations
Cia ib saib
Phiaj foundations rau thaum yau chiv mob hawb pob
Hawb pob yog tshwm sim los ntawm tej thiab caj influences thaum lawv tseem, tab sis, rau tej yam yuav tsis to taub. Ib qhov "ntaus" kuaj tau nyob rau hauv ib cov koom haum genome-dav scan (GWAS) for childhood asthma led a client to believe that one gene might be partially responsible. Tseeb tiag tias no cov koom haum caj yeej yog ua rau mob hawb pob heev, Txawm li cas los, nyuaj. Firstly, [...]
Muab tso rau hauv Phiaj foundations
Cia ib saib
Chaw tsom xam cov ntaub ntawv qhia noob – txiv neej txo fertility / sterility
A group of animals that can breed and produce fertile offspring is one of the definitions of a species. This means that the biological mechanisms of fertility and infertility are of interest not only to evolutionary biologists, but also to clinicians and of course to the wider public. At the Institute of Molecular Genetics in [...]
Muab tso rau hauv Chaw tsom, Phiaj foundations
1 Teb
Phiaj foundations nyob rau hauv cov noob nqaij tsis muaj zog
Leeg tsis muaj zog yuav ua los ntawm ib tug tsis tshua muaj noob kab mob hu ua myofibrillar myopathy. Gonzalo Blanco’s team found a mouse model of this disease and wanted to identify the underlying cause of the severe muscle weakness. Lawv tsom tau los nrhiav tej tshuaj rua lub hom phaj los txhais lus rau kev tshawb fawb soj ntsuam muaj menyuam mus saib thiab soj ntsuam. Ua ntej kuv ua koom tes, the disease had [...]
Muab tso rau hauv Phiaj foundations
Cia ib saib
