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	<title>Efeitos de genes &#187; Alvo descoberta</title>
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		<title>Assim, What Do Your Genes DO?</title>
		<link>http://www.gene-effects.co.uk/pt/2013/so-what-do-your-genes-do/</link>
		<comments>http://www.gene-effects.co.uk/pt/2013/so-what-do-your-genes-do/#comments</comments>
		<pubdate>Tue, 12 Nov 2013 20:20:59 +0000</pubdate>
		<dc:creator>Paul Denny</dc:creator>
				<category><![CDATA[Modelos de doenças]]></category>
		<category><![CDATA[Genômica]]></category>
		<category><![CDATA[Alvo descoberta]]></category>

		<guid ispermalink="false">http://www.gene-effects.co.uk/?p=604-pt</guid>
		<description><![CDATA[Genes are not passive. &amp;nbsp;They are the target of molecular &#8220;dimmer switches&#8221;; typically (but not always) specific proteins, which dial up or turn down their activity. &amp;nbsp;Most genes are translated into proteins, but discovering the true&amp;nbsp;role of&amp;nbsp;those proteins, in the life of a cell or a whole organism, is still one of the great challenges [...]]]></description>
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		<slash:comments>0</slash:comments>
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		<title>Como é que uma mutação em uma transcrição orelha colada fator causal?</title>
		<link>http://www.gene-effects.co.uk/pt/2012/how-does-a-mutation-in-a-transcription-factor-cause-glue-ear/</link>
		<comments>http://www.gene-effects.co.uk/pt/2012/how-does-a-mutation-in-a-transcription-factor-cause-glue-ear/#comments</comments>
		<pubdate>Mon, 17 Sep 2012 14:01:22 +0000</pubdate>
		<dc:creator>Paul Denny</dc:creator>
				<category><![CDATA[Análise Caminho]]></category>
		<category><![CDATA[Alvo descoberta]]></category>

		<guid ispermalink="false">http://user39522.vs.easily.co.uk/?p=355-pt</guid>
		<description><![CDATA[A otite média aguda, sometimes known as “glue ear”, is the most common bacterial infection in children and by 1 ano de idade, cerca de 60% de crianças terão tido um episódio de. Em alguns casos, children develop a chronic condition, que, apesar de a infecção ser curada, o &#8220;cola&#8221; doesn&#8217;t go away and causes deafness.  In an [...]]]></description>
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		<title>A descoberta de destino no início na infância asma</title>
		<link>http://www.gene-effects.co.uk/pt/2012/target-discovery-in-childhood-onset-asthma/</link>
		<comments>http://www.gene-effects.co.uk/pt/2012/target-discovery-in-childhood-onset-asthma/#comments</comments>
		<pubdate>Thu, 06 Sep 2012 10:25:22 +0000</pubdate>
		<dc:creator>Paul Denny</dc:creator>
				<category><![CDATA[Alvo descoberta]]></category>

		<guid ispermalink="false">http://www.gene-effects.co.uk/?p=418-pt</guid>
		<description><![CDATA[Asthma is caused by a combination of environmental and genetic influences, mas os elementos específicos são mal compreendidos. Um &quot;hit&quot; significativa detectada em um genoma de associação ampla varredura (GWAS) for childhood asthma led a client to believe that one gene might be partially responsible. Provando que esta associação genética realmente estava causando asma foi, contudo, difícil. Em primeiro lugar, [...]]]></description>
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		<slash:comments>0</slash:comments>
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		<item>
		<title>Análise de caminho de dados de expressão gênica &#8211; redução da fertilidade masculina / esterilidade</title>
		<link>http://www.gene-effects.co.uk/pt/2012/pathway-analysis-of-gene-expression-data-male-reduced-fertility-sterility/</link>
		<comments>http://www.gene-effects.co.uk/pt/2012/pathway-analysis-of-gene-expression-data-male-reduced-fertility-sterility/#comments</comments>
		<pubdate>Tue, 21 Aug 2012 07:30:18 +0000</pubdate>
		<dc:creator>Paul Denny</dc:creator>
				<category><![CDATA[Análise Caminho]]></category>
		<category><![CDATA[Alvo descoberta]]></category>

		<guid ispermalink="false">http://localhost:8888/?p=246-pt</guid>
		<description><![CDATA[Um grupo de animais que podem se reproduzir e produzir descendentes férteis é uma das definições de uma espécie. Isto significa que os mecanismos biológicos de fertilidade e infertilidade são de interesse não só para os biólogos evolucionistas, mas também para os médicos e, claro, para o público em geral. At the Institute of Molecular Genetics in [...]]]></description>
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		<slash:comments>1</slash:comments>
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		<title>A descoberta de destino em fraqueza muscular hereditária</title>
		<link>http://www.gene-effects.co.uk/pt/2012/target-discovery-in-inherited-muscle-weakness/</link>
		<comments>http://www.gene-effects.co.uk/pt/2012/target-discovery-in-inherited-muscle-weakness/#comments</comments>
		<pubdate>Fri, 03 Aug 2012 18:56:57 +0000</pubdate>
		<dc:creator>Paul Denny</dc:creator>
				<category><![CDATA[Alvo descoberta]]></category>

		<guid ispermalink="false">http://localhost:8888/?p=137-pt</guid>
		<description><![CDATA[A fraqueza muscular pode ser causada por uma doença hereditária rara chamada miopatia miofibrilar. Gonzalo Blanco’s team found a&amp;nbsp;mouse model of this disease&amp;nbsp;and wanted to identify the underlying cause of the severe muscle weakness. Seu objetivo era descobrir potenciais alvos terapêuticos para traduzir em estudos pré-clínicos e clínicos. Antes de eu me envolvi, the disease had [...]]]></description>
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