Maandelijks Archief: September 2012

Hoe werkt een mutatie in een transcriptiefactor oorzaak lijm oor?

Acute otitis media, sometimes known as “glue ear”, is the most common bacterial infection in children and by 1 year of age about 60% of children will have had one episode. In some cases, children develop a chronic condition, which, despite the infection being cured, the “glue” doesn’t go away and causes deafness.  In an [...]

Geplaatst inPathway-analyse, Target discovery | Plaats een reactie

Target discovery in childhood-onset asthma

Asthma is caused by a combination of environmental and genetic influences, but the specific factors are poorly understood. A significant “hit” detected in a genome-wide association scan (GWAS) for childhood asthma led a client to believe that one gene might be partially responsible. Proving that this genetic association really was causing asthma was, however, difficult. Firstly, [...]

Geplaatst inTarget discovery | Plaats een reactie
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