Genes are not passive. They are the target of molecular “dimmer switches”; typically (but not always) specific proteins, which dial up or turn down their activity. Most genes are translated into proteins, but discovering the true role of those proteins, in the life of a cell or a whole organism, is still one of the great challenges [...]
Kategori-arkiv: Disease Models
Så, What Do Your Genes DO?
Også kategorisert under Genomics, Target discovery
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Noen av våre gener mangler…men hvilke?
One can think of genes in a number of ways: På nivået av DNA – rett og slett som en lineær sekvens av nukleotider, i en fast rekkefølge, i “normal” stat, or Again as a DNA molecule, men husk at gener i organismer, i stedet for i stykker av DNA i et reagensrør, are subject [...]
Også kategorisert under Genomics
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Hva kan en liten mus lære oss om menneskelige medfødte misdannelser?
Mice are born with their eyes tightly shut, opening them for the first time only a few days later. So when a mouse was noticed that was smaller than normal and had been born with it’s eyes open, it drew attention. Abnormalities like this arise spontaneously in all animal facilities, but sometimes they are not [...]
Kategorisert under Disease Models
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