A group of animals that can breed and produce fertile offspring is one of the definitions of a species. This means that the biological mechanisms of fertility and infertility are of interest not only to evolutionary biologists, but also to clinicians and of course to the wider public. At the Institute of Molecular Genetics in [...]
Monthly Archives: August 2012
Pathway analysis of gene expression data – male reduced fertility / sterility
Posted in Pathway analysis, Target discovery
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Target discovery in inherited muscle weakness
Muscle weakness can be caused by a rare inherited disease called myofibrillar myopathy. Gonzalo Blanco’s team found a mouse model of this disease and wanted to identify the underlying cause of the severe muscle weakness. Their aim was to discover potential therapeutic targets to translate into pre-clinical and clinical studies. Before I became involved, the disease had [...]
Posted in Target discovery
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